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(c) The model built on females with AS and female controls using 17 female specific analytes (left) does not yield a separation when predicting AS in males (right).
This is a standard statistical technique for characterizing data variances.
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Methods: Twenty-four rats were randomly divided into four groups: Group Con (control), Group Sal (physiological saline), Group Fin (oral finasteride), and Group Bp (oral finasteride and Bp).
The dry eye model was established in group Fin and group Bp.
Aqueous tear quantity was measured with phenol red-impregnated cotton threads with anesthesia.
Results: Finasteride administration effectively induced dry eye in rats by 14 days after administration.
Group Fin rats had significantly higher fluorescein staining scores and lower aqueous tear quantity and BUT than the group Con rats, and notable inflammatory cell infiltrates were observed in the lacrimal gland of group Fin rats.
Red typeface and encircled area indicates cytokines and inflammatory factors.